A clinical trial in the United States had been able to increase survival rates by six months, and an international clinical trial – coming to Australia and New Zealand next year – would pair this drug with a different one in the hope of increasing it further still.
Since focusing his attention to DIPG following the death of his daughter, Dun said their research group had made great progress – and the money raised by Jemima would be a great contribution.
“Our group has gone from one DIPG researcher to seven, and this will continue that, it will continue us to keep moving forward,” he said.
“In three and a half years we’ve gone from having no new treatments to identifying two new drugs for DIPG.
“We’ve had one completed trial and we’re about to start another huge clinical trial that’s international.”
Conducting clinical trials and growing the cancer cells in the lab were both “hugely expensive”.
“If you think about employing one person at the academic level, it costs $120,000 or $130,000 a year,” he said.
“And unfortunately DIPG is unlike any other cancer – to grow them in the lab you have to feed them proteins and media that come from human background … it requires lots of people and lots of time and money.”
With limited government funding, this money usually came from the families of patients, Dun said.
“Families are driving everything in terms of the disease, families are responsible for all the major breakthroughs in DIPG and continue to be,” he said.
“Because it’s such a devastating course, when everything’s said and done it is a real motivator to try and make sure other families don’t have to go through such a hopeless situation.”
Dr Matt Dun says their research is “hugely expensive” and mostly funded by families.
Dun thanked the New Zealand public for their generous donations, and said the funds would help drive their research.
“We’re really grateful for Jemima’s thoughts and all her hard effort in raising this money, and it will be used to really push our programme,” he said.
“And we hope this initial clinical trial will provide a bit more time for families, and we can really push the boundaries on how we can get long-term survivors.
“We need independent scientists with their own ideas to crack this – this is the biggest mountain in medicine.”
To donate to Jemima’s cause, please visit Givealittle.